OR8U8 Rabbit Polyclonal Antibody, 20ul Protein Modification The encoded protein contains a

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

Expression of the encoded protein is induced upon activation of T lymphocytes

This gene is overexpressed in some lung cancers and is linked to poor patient survival

The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs)

and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain)

OR8U8 Rabbit Polyclonal Antibody, 20ul Protein Modification The encoded protein contains a